THE STUDY OF ACUTE AND SUBCHRONIC TOXICITY OF THE DRUG BAKSERGEL
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Keywords

drugs, toxicity, skin-resorptive, local irritant, sensitizing effect, anaphylactogenic, cumulative, allergenic effects

How to Cite

Kamilova, I. (2019). THE STUDY OF ACUTE AND SUBCHRONIC TOXICITY OF THE DRUG BAKSERGEL. Herald of Tashkent Medical Academy, (3 (31), 82-84. Retrieved from http://www.tma-journals.uz/index.php/ttaa/article/view/58

Abstract

Objective: To assess the acute and subchronic toxicity of the new drug anti-inflammatory agent Baksergel. Material and methods: acute toxicity assessment, skin resorptive action, local irritant effect on the skin and irritant action on the mucous membranes of the eyes, as well as determination of the sensitizing effect and cumulative properties of the new drug anti-inflammatory agent Baksergel, which consists of silver nanoparticles - 0.001% and carboxymethylcellulose (CMC) - 2.0%. Results: According to the results of acute and subchronic toxicological studies, the low toxicity of the domestic drug based on silver Baksergel, the absence of skin resorptive, local irritant, sensitizing, anaphylactogenic effect, the absence of cumulative effect was established. Conclusions: The new domestic drug agent Baksergel recommended for widespread clinical use in various fields of medicine. Conclusions: The new domestic drug agent Baksergel recommended for widespread clinical use in various fields of medicine.

PDF (Русский)

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